Platelet-rich fibrin injections help stimulate stem cells which improve collagen and elastin in the skin. PRF can be injected into several areas of your face to help with dark circles, tear troughs and deep folds, volume loss, wrinkles, and fine lines. A series of 4 initial monthly treatments are recommended with a 6-month touch-up, then annual sessions for maintenance. You may see a slight improvement after your first or second session but you should see the optimal results after 4 sessions.